This centers-based lesson on multiples is designed for two-days of 45-minute lessons or one-day of a 90-minute lesson block. The lesson provides differentiated instruction using the H.O.P. Centers Framework. H.O.P. stands for Hands-On, Open-Ended, and Practice which are the themes for each of the three centers in the framework. Lesson structure is designed using brain research principles. In this lesson students will learn how to find the multiples of a number with a short engaging lesson, hands-on activity in which students group counters to create their own multiples, practicing writing about a word problem using multiples, and engage in tiered practice of the concept.