The operon model was proposed by Jacob, Monod, and Wollman based on studies on lactose-requiring mutations of E. coli. In this problem set you will work with the types of genetic and biochemical information used to unravel the inner workings of the lac operator-repressor regulation system.

Instructions: The following problems have multiple choice answers. Correct answers are reinforced with a brief explanation. Incorrect answers are linked to tutorials to help solve the problem.

1. Components of the lac operon of E. coli

2. The role of the inducer of the lac operon

3. Phenotype of lac Z- E. coli cells

4. Exchange of genetic information between bacteria

5. DNA transfer by an F factor

6. Different alleles for a bacterial genes

7. Regulation of lac Z gene on an F' episome

8. The Oc mutation of the lac operon

9. Phenotype of lac I- cells

10. Phenotype of cells diploid for lac I gene

11. The effect of high glucose on lac operon expression

12. Effect of high glucose concentrations

13. Effect of high lactose and low glucose on lac operon

14. Effect of the absence of glucose

This resource is part of the Biology Links for One Laptop Per Child course which contains units on Exploring Life; The Cell; Genetics; Mechanisms of Evolution; The Evolutionary History of Biological Diversity; Plant Form and Function; Animal Form and Function; Ecology; and Astrobiology.

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